Solid Waste Recycling in Textile Processing Industries: A Case Study of India’s Clothing Hubs

This study investigated the type and amount of solid waste generation from textile wet processing industries and analyzed the disposal and recycling strategies implemented for its utilization. The method involved industrial interactions with textile processing mills. Data was gathered based on a field survey of manufacturing units and their compliance management teams. The solid waste generated in textile processing stages against input raw materials and fuel sources was recorded. The challenges in recycling solid waste are identified and further scope for its valorization is suggested. The results indicate that significant solid waste produced during the wet processing of textiles arises from waste fabric cuttings, combustion of fuels used in processing stages, and sludge generated from the post-effluent treatment. Around 80% of solid waste generated during the wet processing of textiles can find applications in the construction industry. Effective management of solid waste and its potential applications in construction are elaborated in detail.

A Review on Design of Sustainable Advanced Materials by Using Artificial Intelligence

This paper gives a comprehensive review of scientific interests and current methodologies of artificial intelligence applied to advanced material design and discovery by taking into account multiple sustainable design criteria such as functionalities, costs, environmental impacts, and recyclability. The main research activities include predicting material properties, compositions, and structures with data mining, new material discovery, hybrid modeling approaches combining AI techniques and classical computational formulations based on physical and chemical laws, and multicriteria optimization of materials. Based on this review, a short analysis is provided on the perspectives of this research area in the future, aiming at creating an everything connected material life cycle with real-time traceability systems

A Novel Animal Model for Pulmonary Hypertension: Lung Endothelial-Specific Deletion of Egln1 in Mice

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by high blood pressure in the pulmonary arteries, which can potentially lead to heart failure over time. Previously, our lab found that endothelia-specific knockout of Egln1, encoding prolyl 4-hydroxylase-2 (PHD2), induced spontaneous pulmonary hypertension (PH). Recently, we elucidated that Tmem100 is a lung-specific endothelial gene using Tmem100-CreERT2 mice. We hypothesize that lung endothelial-specific deletion of Egln1 could lead to the development of PH without affecting Egln1 gene expression in other organs. Tmem100-CreERT2 mice were crossed with Egln1^flox/flox mice to generate Egln1^f/f;Tmem100-CreERT2 (LiCKO) mice. Western blot and immunofluorescent staining were performed to verify the knockout efficacy of Egln1 in multiple organs of LiCKO mice. PH phenotypes, including hemodynamics, right heart size and function, pulmonary vascular remodeling, were evaluated by right heart catheterization and echocardiography measurements. Tamoxifen treatment induced Egln1 deletion in the lung endothelial cells (ECs) but not in other organs of adult LiCKO mice. LiCKO mice exhibited an increase in right ventricular systolic pressure (RVSP, ~35 mmHg) and right heart hypertrophy. Echocardiography measurements showed right heart hypertrophy, as well as cardiac and pulmonary arterial dysfunction. Pulmonary vascular remodeling, including increased pulmonary wall thickness and muscularization of distal pulmonary arterials, was enhanced in LiCKO mice compared to wild-type mice. Tmem100 promoter-mediated lung endothelial knockout of Egln1 in mice leads to development of spontaneous PH. LiCKO mice could serve as a novel mouse model for PH to study lung and other organ crosstalk.

Efficacy and Cytocompatibility of a Pressure Garment—Silicone Composite Dressing Material for Scar Healing

Pressure garment therapy (PGT) and silicone gel sheeting (SGS) predominate non-invasive interventions for burn injuries, but the market lacks a composite solution combining pressure garment fabric (PGF) and medical-grade silicone (e.g. Biopor®AB) for multi-therapeutic efficacy. To address this gap, a versatile composite dressing of PGF-Biopor®AB was developed. PGF-Biopor®AB incorporates dual PGF-SGS therapy, mechanotherapy, and active moisture management, to facilitate recovery of hypertrophic subsidiary structures. The PGF structure enables the application of PGT, while the Biopor®AB silicone characteristics enforce silicone gel therapy (SGT). The PGF-SGS efficacy optimization not only reduces tension but also facilitates water vapor and oxygen penetration, along with hydration of the stratum corneum. Mechanotherapy, involving tension-shielding and pressure redistribution, promotes the reorganization of the collagen-fiber network. For active moisture management, the incorporation of a microchannel structure with active nylon absorbency facilitates effective moisture control through water absorption, retention, and cellular pathways of transport. In this study, the microscale features in the structure were further investigated. Under ISO 10993-5 standard, an over 70% cell viability in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay containing the L929 cell line verified the enhanced cell growth and inhibited proliferation, endorsing the safe usage of PGF-Biopor®AB. Patient studies of one-month efficacy in both high and low-cell-density samples and an early scarless healed wound suggest that over 70% cell viability is sufficient for optimal scar therapeutics. The multifaceted scar repair roles are fulfilled by addressing persistent inflammation, insufficient oxygenation, low levels of perfusion, and scar-healing tension, hence realising the multi-therapeutic efficacy of the composite dressing.

The Strange Question of Species: Biocratic Implications in Interwar Paleoanthropology

Species was one of the most controversial concepts in biological science. Not even the “New Systematics” of the 1930s and 1940s succeeded in bringing complete clarity to the issue. During the first half of the twentieth century the conceptualization of species was challenged by paleontology, a then-emerging discipline, but an ancient essentialist conception resisted, whereby each species is characterized by its own immutable essence (eidos). This simplification was transferred to physical anthropology in the study of human populations, with further cultural and political outcomes. For example: the meaning of species developed a series of biopolitical and legal implications regarding the construction of a society preserved from foreign dangerous bodies. From this perspective, the racial policy of the Third Reich established that the German national community was to be based on belonging to a same species (Art), from which Jewish population was excluded, considering it an alien species (Artfremd) and therefore incompatible. The concept of species, defined from an essentialist perspective, was in fact considered more differentiating and selective than that of “race”. Consequently, foreignness to the human species became a more radical distinguishing factor than racial classification. The article, with a focus on German academia, aims to reconstruct the debate in paleoanthropology during interwar period.

Current Progress on Microbial l-malic Acid Production

As an important intermediate in the tricarboxylic acid (TCA) cycle, l-malic acid (l-MA) is also one of the 12 important platform bulk chemicals with high added value. Owing to its various applications in food, pharmaceuticals, cosmetics and industry, the global l-MA market size is growing year by year. Over the last few decades, increasing concerns regarding fossil fuels depletion and excessive CO₂ emissions have led the global commitment to fostering a green economy and sustainable development. Alternatively, the sustainable microbial fermentation of l-MA has gradually attracted more and more attention. Here, this review summarizes the common l-MA biosynthesis pathways and compares the differences between different chassis microorganisms as well. Moreover, regulation strategies of genetic metabolic engineering and fermentation process to boost the l-MA production are summarized, and the research status of l-MA production from the cheaper substrates is also discussed. Finally, the direction of further exploration of industrialized l-MA biosynthesis is proposed, which provides a theoretical guidance on promoting technological innovation in industrial l-MA production.

Proposal for A Systemic Human Ecological Turn for Health Science and Medicine

Industrial development processes, accompanied by extreme growth processes, regards world population, pollution, food production and the exploitation of natural resources have caused severe ecological problems. This has been well known since 1972 through the study ‘The Limits to Growth’, in which humanity and the world society was called upon to make an ecological turn and to change its consumption model and the type of economic development that was not suited to finite natural resources (or a finite planet). However, the relationships between the state of the environment and human health have hardly been considered, although an ecological view of health was already proposed by Hippocrates, and as in the meantime, the technical terms “Environmental Health” and “Environmental Medicine” have become established at universities. It is only in recent times that global terms such as climate medicine, One Health, Eco Health, etc. have become powerful pragmatic and action-oriented initiatives. They can be understood as calls for a worldwide health-related ‘ecologization’ of (health) culture. Regarding these approaches we highlight theoretical and metatheoretical aspects, since in general, any real action is only as good as the analytical quality of the plan that serves as a guide for that action. From this point of view, we find that these approaches exhibit striking weaknesses. These are, among other things: the neglect of epistemological challenges combined with inconsistent conceptualizations of the category environment, the very superficial models of human beings, weaknesses of ecological frameworks in relation to the macro-, meso- and micro-eco-social levels of the targeted topics, and a vague notion of systems methodology. Following on from this, we call for an explicit social-/human-ecological framework (New Viennese School, Australian School) for environmental health issues as it has been established for decades in the field of environmental, sustainability and transformation sciences.

Numerical Study on Pyrolysis Characteristics of Oil-Based Drilling Cuttings in a Two-Layer Screw-Driving Spiral Heat Exchanger

Oil-based drilling cuttings is a pollutive nearly-solid waste produced in oil exploitation that has to be treated for meeting clean production requirement of oil and gas exploration. A two-layer screw-driving spiral heat exchanger was thus proposed for this purpose. To investigate its effectiveness and performance, a 10-component n-decane one-step product proportional distribution chemical model was used to describe oil-based drilling cuttings pyrolysis process, and numerical simulations were carried out of forced convection inside the heat exchanger with a full consideration of pyrolysis and evaporation effects. The influences of rotation speed, screw pitch and cross-sectional shape of spiral tube on pyrolysis, flow, and heat mass transfer characteristics were studied. The results show that the heat absorbed needed for evaporation is much less than that for pyrolysis, and the heat transfer coefficient with consideration of evaporation and pyrolysis is almost two times greater than that without. The pyrolysis rate increases first, and then decreases once the temperature is higher than 838 K due to the coupled effects of temperature and reactant concentration change. The velocity, heat transfer coefficient and conversion ratio of oil-based drilling cuttings all increase with rotation speed, but the conversion ratio increase becomes slower and slower once the rotation speed exceeds 0.2 rad·s⁻¹. The average vorticity and flow resistance of oil-based drilling cuttings both decrease with screw pitch monotonously, while heat transfer coefficient increases first and then decreases because of the opposite effects of centrifugal force and thermal entrance length. Reducing screw pitch can increase conversion ratio, but once screw pitch is smaller than 800 mm, the conversion ratio approaches to a constant. Cross-sectional shape of spiral tube also affects pyrolysis performance, and circular cross-sectional spiral tube seems to be the best.

Advancements in the Bio-degradation of Plastic Waste into Value-added Chemicals: A Recent Perspective

Plastics are an essential component of modern life, but the plastic waste has caused significant environmental pollution and economic losses. The effective solution to these problems is the biodegradation and high-value conversion of plastic waste. After biodegradation, plastic waste is broken into smaller molecules and eventually transformed into innocuous substances like water, carbon dioxide and biomass. High-value conversion enables plastic waste to be converted into products with higher economic value and environmental friendliness. Based on this, we summarize the biodegradation methods of bioplastics and analyze the shortage of these methods. Subsequently, we summarize the progress of converting the degradation products into value-added chemicals, comprehensively analyze the advantages and disadvantages of these bioconversion process, and propose some strategies to address these disadvantages. Finally, we analyze the significance of establishing a microbial-based conversion process that integrates the degradation and the conversion, and propose some potential strategies.

Reply to Sarmiento E. “Australopithecine Taxonomy and Phylogeny and the Savanna Hypothesis; Comment on Vaneechoutte et al. Have We Been Barking up the Wrong Ancestral Tree? Australopithecines Are Probably Not Our Ancestors. Nat. Anthropol. 2023, 2, 10007”